top of page
Copy of Reimb for Computer-aided mapping

DYSIS Announces Medicare Reimbursement Rates for the New Add-On CPT Code 57465, Which Can Be Used for DYSIS Smart Colposcopy, Effective January 2021

DYSIS Smart Colposcopy is computer-aided cervical imaging that adds the DYSISmap to a standard colposcopic assessment with clinical studies showing that it helps clinicians increase detection of high-grade cervical lesions.

December 3, 2020 — ALPHARETTA, Georgia — DYSIS Medical, Inc. announced today that the Centers for Medicare and Medicaid Services (CMS) issued their 2021 Medicare Physician Fee Schedule  (PFS) that now includes reimbursement rates for Add-On CPT® Code 57465 (computer-aided mapping of cervix uteri during colposcopy, including optical dynamic spectral imaging and algorithmic quantification of the acetowhitening effect) under which DYSIS Smart Colposcopy with DYSISmap™ is billed.  The payment rate for the new add-on code (57465) will provide for a national average Medicare reimbursement rate of $54.45 (Total Non-Facility RVU 1.68) in the office.   


“I have performed DYSIS colposcopy with the adjunctive DYSISmap on my patients for the past five years, and it has been a tremendous benefit,” said Karen Harris, MD.  Dr. Harris is an Ob-Gyn and Residency Program Director at Women’s Group of North Florida and is Past-District XII chairperson of ACOG. “The added reimbursement for Medicare patients shows the value of this added service, and we look forward to future private payors also reimbursing.”


“The CMS decision to provide reimbursement for computer-aided mapping of the cervix is another important milestone for DYSIS as well as a step forward in the early detection of cervical pre-cancers,” said Darin Hammers, CEO of DYSIS Medical. “Medicare reimbursing physicians for computer-aided mapping of the cervix will help in our goal of increasing patient access to DYSIS cervical mapping technology.”


The unique feature of the DYSIS Colposcope is that it accurately measures the acetowhitening of the cervical epithelium using a proprietary technology called Dynamic Spectral Imaging. The results are summarized in the DYSISmap that is overlaid on the live image of the cervix. The inclusion of the DYSISmap information with the standard colposcopic indications can assist with the identification of cervical disease.  In the IMPROVE-COLPO study, when map-assisted biopsies were added to colposcopy exams, detection of patients with CIN2+ increased by 44%.


Add-on code 57465 can be used in conjunction with primary procedure codes 57420, 57421, 57452, 57454, 57455, 57456, 57460, and 57461. DYSIS Medical will continue its efforts to ensure positive coverage decisions of both public and private payers.     

 DeNardis et al. Int J Womens Health. 2017; 9: 717–725.

CPT® is a registered trademark of the American Medical Association

Document No. 0354-01295





Find out more about Medicare reimbursement for DYSIS Colposcopy

Complete the form below and a member of our team will be in touch.

DYSIS is a registered trademark of DYSIS Medical Ltd.

For additional information on use of the DYSIS Ultra 2.0 including applicable regulations,

please refer to the DYSIS Ultra 2.0 Digital Colposcope Instructions for Use: 0330-53095

bottom of page